Some covid-19 Treatment
suggestions by research
As
we know that there is no cure yet for the pandemic covid-19. Doctors and
scientists are hardly trying to find treatments and drugs that can save the
lives of infected people and perhaps prevent infections. Scientists are
searching for antivirals that work to strictly stop the new coronavirus.
Following are the 16 major treatments suggested by the doctors and
scientists.
Dexamethasone:
- This is a steroid which is nothing but cheap and widely available.
- It candid various type of immune responses.
- It is widely used by the doctors to treat asthma, allergies and
inflammation.
- Another of more than 5-6 thousand
people found that dexamethasone reduced deaths by the ratio 1:3 in patients on
ventilators and 1:5 in patients on oxygen.
Remdesivir:
- It stops viruses from duplicating when it inserting into viral genes.
- It can minimize hospital stay in severe cases from 15-11 days.
- It can’t fight Ebola and Hepatitis C.
- According to latest data it might reduce death rates among those who are
very ill.
Fig.2 Remdesivir
Fevipiravir:
- Fevipiravir is nothing but a flu drug.
- This flu drug is able to blocks a virus’s ability to copy its genetic
material.
- Its clinical trials are still pending.
Recombinant Ace-2:
- Ace-2 is nothing but a human protein.
- Recombinant Ace-2 is an artificial protein.
- The coronavirus enters a cell by latching on to a human protein known as
Ace-2; Recombinant Ace-2 proteins might be able to lure it away from vulnerable
cells.
- They have shown promising results in experiments on cell but not yet in
living beings (people and animals).
Eidd-2801:
- It is an antiviral that really designed to fight the flu.
- It has promising results against the novel coronavirus in studies in
cells and on animals.
- Eidd-2801 is still being tested in humans.
Convalescent plasma:
- A century ago, Plasma from the blood of recovered flu patients used by
the doctors to treat people sick with flu and this method is known as plasma therapy.
- Same strategy has been tried on people severely sick with flu like
covid-19 and the early results are promising.
- Convalescent plasma contains a mix of antibodies.
- This plasma therapy has been authorized by the US food and drug authority
(FDA) for very sick covid-19 patients.
Monoclonal antibodies:
- Convalescent plasma contains a mix of antibodies, only some of them can
fight the novel coronavirus.
- Most potential covid antibodies and their copies called as monoclonal
antibodies.
- It can be manufactured in bulk and injected into patient.
- Safety trials for this treatment have only just begun.
Interferons:
- The molecules that our cell produces to make
the immune system attack and stop viruses, those molecules are called interferons.
- It is a standard treatment for immune
disorders to injecting interferons.
- Experiments have done in mice and cells;
suggest that interferons injections could be used both as preventive and a
treatment for covid-19.
Cytokine inhibitors:
- Cytokines are nothing but the molecules which
produced by our body.
- These produced cytokines fight off the
disease.
- But in excess they can trigger cytokine storm
leads the immune system to overreact to infections.
- To halt those cytokine storms researchers
have created several drugs like tocilizumab, sarilumab, and anakinra.
- A few have offered modest help in some
trials, others have faltered.
- The drug company Regeneron recently announced
that a branded version of sarilumab, Kevzara, failed 3rd phase of clinical
trial.
Cytosorb:
- It is nothing but a cartridge.
- The function of cartridge is to filters
cytokines from the blood in an attempt to cool or moderate cytokine storms.
- This machine can purify a patient’s entire
blood supply.
- Purification process of blood supply by
cartridge is about 70 times in a 24-hour Period.
Stem cells:
- Certain type of stem cells can undisclosed or
hide anti-inflammatory molecules.
- These hidden anti-inflammatory molecules used
to treat cytokine storm by the researchers.
- Dozens of clinical trial are under way to see
if they can help coronavirus patients.
- Stem cell treatments have not worked well in
the past.
Anticoagulants:
- Coronavirus can attack cells in the lining of
blood vessels, which causes to tiny clots that can cause strokes.
- Anticoagulants are commonly used to moderate
or slow the formation of those tiny clots.
- Doctors sometimes use them on covid-19
patients with clots.
Lopinavir-ritonavir:
- This is the combination of HIV drugs.
- At first this drugs seemed to stop covid-19
from replicating.
- After clinical trial on patients prove
disappointing.
- WHO suspended this drug for a while, nearly
one month.
- The drugs might play an important role as a
preventive and in treating patients with mild symptoms.
Hydroxycloroquine and chloroquine:
- This is an old malaria drugs.
- At start of covid-19 researchers found that
these drugs could stop coronavirus from replicating in cells.
- After randomized clinical trials it is clear
that this drug didn’t help people with covid-19 get better or prevent healthy people
from contracting the coronavirus.
- This drug didn’t reduce the severity of the
covid-19 patients’ right after the diagnosis of the patients.
- According to the US FDA warns that the drug
cause side effects to heart and other organs when it used to treat covid-19
patients.
Prone positioning:
- This is one type of method and widely used to
treat covid-19 patients.
- Under this method covid -19 patients have to
flip their body on to their bellies to conveniently open up the lungs.
- The method might help some individuals avoid
the need for ventilators entirely.
Ventilators:
- Ventilators are nothing but essential devices
that help people breathe.
- Its function is to supply of oxygen through
the nose or via a mask.
- That mask or nose connected to an oxygen
machine.
- Patients in severe respiratory distress may
need to have a ventilator breathe for them until and unless their lungs heal.
(Md Muzammil
Alam)
Thanks for ds information
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